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Infectivity


Q-A 1

Q (t) I read in various website that the mouth mucosa is permeable, independently of the presence of lesions. May the HIV penetrate a mucosa without lesion ?
If yes, is it capable to reach a blood vessel ?

You also said that the HIV is fragile in the air : for instance a guy that comes in the evening, if he doesn't wash himself, often observes white traces at the base of the glans. Are these trace contaminating, in case of fellatio for instance ?

A (t) Concerning fellatio, the risk of HIV transmission is possible in case of a bleeding lesion, like gingivitis, or even just after a teeth brushing. But the lesion may be microscopic, giving a non visible bleeding. To our knowledge, the HIV cannot penetrate a mucosa without lesion.

Taking about mucosa permeability, or skin permeability, means that, indeed, these surfaces are not continuous, and exchanges from one side to the other are possible. Indeed, the majority of the skin surface is not continued by skin, but by empty spaces, wich are the scene of important exchanges with the outer.
Concerning the fragility of the HIV in the air, this notion is based on the fact that it is much more fragile than other viruses, like HBV or HCV (this is why it is much more probable to be infected by this two viruses, when stung by a needle on a beach, than with the HIV).
Until now, the contaminating power of the HIV was evaluated by measuring the reverse transcriptase activity : it has been shown that a solution containing 100,000 times more virus than in the blood of contaminated person, after a 56°C heating of 30 minutes, keeps an infecting power during three hours.
Concerning the risk of contamination from dried sperm containing HIV, its infecting power is certainly diminued; but only biological measurements could tell us in wich proportion (we could no find any publication on this particular subject); a fellatio made in these conditions could present a risk, if there is a bleeding lesion in the mouth, even invisible. (9711)



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