C.6. DRASTIC INCREASE OF CD4 CELL COUNTS

BY CHAM3 THERAPY IN HIV INFECTED PATIENTS

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A. CAPRANI°, B. MIRAMOR*, J. AVICENNE°, A. RICHERT°,
E. RITA DE LIMA TEIXEIRA
° Association "Positifs" BP 230 75865 Paris Cedex 18 (France),
[E.mail: positifs@positifs.org, internet: http://www.positifs.org],
* Caixa Postal 1394, Salvador Bahia (Brazil) CEP 40001 - 970,+ Policlinica Santa Paula, 2717 Av. Presidente Vargas - Ondina, Salvador Bahia (Brazil).

OBJECTIVE

To test the efficiency of an herbal preparation of a mixture of 3 brazilian plants (CHAM3) on HIV+ patients.

METHOD

ð Open trial (trial duration 9.23 months)
ð 12 brazilian HIV patients (5 ARC and 7AIDS)
ð 1992 - 1995
ð posology: 100 ml 3 times a day of CHAM3 solution (about 1g/l of plant extract).

RESULTS

ð Drastic improvement of clinical and biological parameters for all patients
ð No opportunistic infection
ð No side effects

parameter

before therapy
(mean+/-SD)

after therapy
(mean+/-SD)

significancy

p value Hb (g/l)

 12.38+/-2.13

12.58+/-2.05

0.97

Leucocytes/mm3

 5080+/-2061

 4801+/-2270

0.75

Lymphocytes/mm3

 1585+/-852

 1811+/-885

0.31

Lymphocytes %

3 2.35+/-13.9

39.33+/-12.8

0.071

CD4 Lymphocytes/mm3

    207+/-186

   460+/-207

0.0025

CD4 Lymphocytes %

12,68 +/-7,65

22,47+/-6,74

0,01

CD8 Lymphocytes/mm3

    853+/-373

   960+/-731

0.72

CD8 Lymphocytes %

  54.1+/-8.2 4

    65+/-11.8

0.07

Monocytes/mm3

 341+/-198

  225+/-118

0.15

patients

1

2

3

4

5

6

7

8

9

10

11

12

cd4/mm3 before

19

45

49

68

93

108

144

274

288

385

396

620

cd4/mm3 after.

554

200

422

289

322

452

243

960

425

635

435

582

CONCLUSION

Cham3 appears to be an efficient agent in HIV infected brazilians patients, particularly in the more depressed ones. A similar investigation is in progress in Europe, in order to confirm or infirm these results.

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© Copyright POSITIFS association, France, 1996.
XI International Conference on AIDS, Vancouver, July 7-12, 1996 abstract 2285.
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