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C.89-EBOLA- INFO Urgente à diffuser-Un anti-HIV(Lamivudine) en traitement précoce, permet la guéris PDF print email
Written by MKG Tran   
Saturday, 11 October 2014 10:56
There are no translations available.

Une incroyable découverte due au hasard: le 3TC(Lamivudine) guérit l'Ebola ; le Dr LOGAN Gobee  (un des 2 médecins au Liberia, pour 85 000 patients), en désespoir de cause, se disant que l'Ebola est un mini-Sida, essaie de son propre chef de traiter ses malades, en particulier un des soignants; il échoue une première fois avec un anti-herpès, mais il essaie une 2ème FOIS AVEC CE QUI LUI TOMBE SOUS LA MAIN : Le 3TC;
Surprise, tous ses malades guérissent (13/13)
2 malades qui prennent le 3TC après le 5ème jour meurent
mais tous ceux qui le prennent avant le 5ème jour sont VIVANTS;
Anthony FAUCI (NIH) est très intéressé.
TRAN MKG a trouvé(non publié) une homologie sur YMDD (Tyr Met Asp Asp), entre HIV-1 et Ebola polymérase , (ainsi d'ailleurs que l'hépatite B polymérase) qui explique pourquoi le 3TC guérit l'Ebola.
Voici le informations diffusées avec trop peu d'échos dans les medias, alors qu'il s'agit de la seule voie thérapeutique accesible aujourd'hui pour stopper l'épidémie pour quelques euros par patient!

EPIDEMIE - Un médecin du Libéria a testé avec succès le lamivudine sur les malades d’Ebola…

Soigner le virus Ebola avec un traitement contre le VIH. L'idée pourrait sembler loufoque,
mais elle a fait ses preuves selon CNN qui a consacré un reportage au docteur Gobee Logan.
Ce médecin du Liberia soigne depuis plusieurs semaines 15 malades de la fièvre hémorragique Ebola avec de la lamivudine, avec des résultats probants.
Cette molécule agit d'habitude sur le virus de l'immunodéficience humaine (VIH).
Tous les malades d'Ebola, sauf deux, ont pour l'instant survécu, ce qui porte à 13% le taux de mortalité (contre 60% en Afrique de l'Ouest).

Les patients avaient été traités dans les cinq jours qui ont suivi l'apparition des premiers symptômes, sauf les deux décédés, traités entre le cinquième et le huitième jour. « Mon estomac me faisait mal, je me sentais faible, je vomissais», témoigne Elizabeth Kundu, 23 ans, l'une des survivantes. «Ils m'ont donné des médicaments et je me sens mieux. Nous pouvons maintenant manger et nous sentir bien dans notre corps.»

Un test dans l'urgence

« Je suis sûr que quand les patients sont traités dès le début, ce médicament peut les aider », affirme Logan. Exerçant dans la région de Tubmanburg dans le nord ouest du Liberia, il aurait testé cette pratique en désespoir de cause, face à l'afflux de malades dans son centre. L'expérience n'est pas scientifique puisqu'aucun protocole de test n'a été respecté (placébo, essai en double aveugle).
Mais dans l'urgence, la lavimudine aurait une action efficace dans la mesure où cette molécule n'est pas éloignée de celles en expérimentation pour Ebola,
comme le nucléoside.

Par ailleurs, le médecin est conscient des effets secondaires occasionnés par le traitement. La lamivudine peut notamment endommager le foie. Mais la vie des patients en dépend...
Résultats de recherche


Liberian Doctor Cures Ebola With HIV Drug Lamivudine [Video ...
newsrescue.com/...cures-ebola-hiv-drug-lamivudine-video   En cache
While the world waits for a proven Ebola drug, he’s experimenting with an HIV drug called lamivudine. “In order for everyone in this unit not to die, I think I ...



Ebola Lamivudine Résultats dans l'actualité
Ebola : Un traitement contre le sida pour sauver les patients?
20minutes.fr via Yahoo! France Actualités 10 heures
Ebola: un médecin a testé avec succès un médicament contre le Sida
Slate 9/28/14, 12:34 PM

.


Apparent success against Ebola with HIV drug in Liberia - CNN.com
www.cnn.com/2014/09/27/health/ebola-hiv-drug/index.html   En cache
A doctor in rural Liberia inundated with Ebola patients says he's had good results with a treatment he tried out of sheer desperation: an HIV drug.


Ebola Lamivudine - Images

Liberian Doctor Cures Ebola With HIV Drug Lamivudine [Video ...


Ebola : la lamivudine, utilisée à titre compassionnel (et peut-être ...


Dr Gobee Logan reports success in treating Ebola with lamivudine


Doctor 'Successfully' Treats Ebola with HIV Drug in Liberia |Nigeria ...


ALiberiandoctor has devised an unusual means of treatingEbolapatients ...


Doctor treats Ebola with HIV drug in Liberia -- seemingly successfully ...


... means of treating Ebola patients and he has achieved partial success

Plus d'images pour Ebola Lamivudine.


Ebola Breakthrough?
www.dailykos.com/story/2014/09/27/1332809/-Ebola...   En cache
Dr. Gobee Logan, a doctor in rural Liberia, has given an HIV drug, lamivudine, to 15 Ebola patients. 13 survived. Continue past the mating paramecium for more:



JIM.fr - Ebola : la lamivudine, utilisée à titre ...
www.jim.fr/medecin/actualites/pro_societe/e-docs/ebola...   En cache
Paris, le lundi 29 septembre 2014 – Il est difficile de mesurer le sentiment de dépassement éprouvé par les équipes médicales qui font face à l’épidémie d ...



Doctor treats Ebola with HIV drug in Liberia | Health - KTUU ...
www.ktuu.com/news/health/doctor-treats-ebola-with-hiv...   En cache
Dr. Gobee Logan has given the drug, lamivudine, to 15 Ebola patients, and all but two survived. That's a 7% mortality rate. Across West Africa, the virus has killed ...



Ebola outbreak: Liberia doctor treating patients with HIV ...

www.independent.co.uk  › News  › World  › Americas

A desperate doctor in rural Liberia who resorted to treating his Ebola patients with a HIV drug claims the mortality rate at his clinic has dropped to just seven per ...



Ebola traité avec un médicament anti-sida

www.lefigaro.fr  › Flash Actu

Un médecin au Libéria a tenté de traiter des patients atteints de la fièvre Ebola avec un médicament anti-sida, et les résultats seraient encourageants.



Doctor treats Ebola with HIV drug in Liberia | Health - Home
www.clickondetroit.com/.../doctor-treats-ebola.../28279604   En cache
A doctor in rural Liberia inundated with Ebola patients says he's had good results with a treatment he tried out of sheer desperation: an HIV drug. Dr. Gobee Logan ...



Doctor treats Ebola with HIV drug in Liberia | Health - Home

www.kvia.com  › News  › Health

A doctor in rural Liberia inundated with Ebola patients says he's had good results ... Gobee Logan has given the drug, lamivudine, to 15 Ebola patients, and all but ...



Ebola Crisis: Liberia Doctor Treats Patients With HIV Drugs ...
uk.news.yahoo.com/ebola-crisis-liberia-doctor...   En cache
'Ebola Crisis: Liberia Doctor Treats Patients With HIV Drugs ... Dr Gobee Logan gave the drug lamivudine to 15 Ebola patients in a clinic in Tubmanburg, ...


Dr. Gorbee Logan tried using lamivudine against Ebola out of sheer desperation
Only two out of 15 patients taking it died -- far lower than the average death rate
Logan read about the medication and similarities between Ebola and HIV in a medical journal



(CNN) -- A doctor in rural Liberia inundated with Ebola patients says he's had good results with a treatment he tried out of sheer desperation: an HIV drug.
Dr. Gorbee Logan has given the drug, lamivudine, to 15 Ebola patients, and all but two survived. That's about a 13% mortality rate.
Across West Africa, the virus has killed 70% of its victims.
Outside Logan's Ebola center in Tubmanburg, four of his recovering patients walk the grounds,
always staying inside the fence that separates the Ebola patients from everyone else.
"My stomach was hurting; I was feeling weak; I was vomiting," Elizabeth Kundu, 23, says of her bout with the virus.
"They gave me medicine, and I'm feeling fine. We take it, and we can eat -- we're feeling fine in our bodies."
Kundu and the other 12 patients who took the lamivudine and survived, received the drug in the first five days or so of their illness.
The two patients who died received it between days five and eight.
"I'm sure that when [patients] present early, this medicine can help," Logan said. "I've proven it right in my center."

Two doctors for 85,000 people

Logan is mindful that lamivudine can cause liver and other problems, but he says it's worth the risk since Ebola is so deadly.
He also knows American researchers will say only a real study can prove effectiveness.
That would involve taking a much larger patient population and giving half of them lamivudine and the other half a placebo.
"Our people are dying and you're taking about studies?" he said. "It's a matter of doing all that I can do as a doctor to save some people's lives."
FDA warns companies about fake Ebola drugs
Logan said he got the idea to try lamivudine when he read in scientific journals that HIV and Ebola replicate inside the body in much the same way.
"Ebola is a brainchild of HIV," he said. "It's a destructive strain of HIV."
At first he tried a drug called acyclovir, which is often given to HIV patients to treat infections that occur with their weakened immune systems.
But it didn't seem to be effective.
Then he tried lamivudine on a health care worker who'd become ill,
and within a day or two he showed signs of improvement and survived.
One woman walked in, and the Ebola nightmare began
Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases says that theoretically, Logan's approach has some merit.
Lamivudine is a nucleocide analog, and other drugs in this class are being studied to treat Ebola.
Fauci asked CNN to give Logan his email address, saying perhaps his lab could do some follow up work.
Logan says he plans to email Fauci this weekend.

CNN's John Bonifield, Orlando Ruiz, and Orlind Cooper contributed to this story.






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Daily Kos     News, Community, Action .PEOPLE GROUPS DIARIES TAGS. LABOR COMICS ELECTIONS ECON RADIO wilderness voiceFollowRSS

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Sat Sep 27, 2014 at 10:59 AM PDT.

Ebola Breakthrough?


by wilderness voiceFollow .

67 Comments / 67 New
.
Dr. Gobee Logan, a doctor in rural Liberia, has given an HIV drug, lamivudine, to 15 Ebola patients. 13 survived.  Continue past the mating paramecium for more:
.
http://www.cnn.com/...

"My stomach was hurting; I was feeling weak; I was vomiting," Elizabeth Kundu, 23, says of her bout with the virus. "They gave me medicine, and I'm feeling fine. We take it, and we can eat -- we're feeling fine in our bodies." Kundu and the other 12 patients who took the lamivudine and survived, received the drug in the first five days or so of their illness. The two patients who died received it between days five and eight.
...
[Dr. Logan] also knows American researchers will say only a real study can prove effectiveness. ..."Our people are dying and you're taking about studies?" he said. "It's a matter of doing all that I can do as a doctor to save some people's lives."
...
Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases says that theoretically, Logan's approach has some merit.... other drugs in this class are being studied to treat Ebola
Lamivudine is a nucleoside analog:
http://en.wikipedia.org/...
These agents can be used against hepatitis B virus, hepatitis C virus, herpes simplex, and HIV. Once they are phosphorylated, they work as antimetabolites by being similar enough to nucleotides to be incorporated into growing DNA strands; but they act as chain terminators and stop viral DNA Polymerase. They are not specific to viral DNA and also affect mitochondrial DNA. Because of this they have side effects such as bone marrow suppression.
Ebola virus uses RNA only and does not create any DNA.  However, RNA requires nucleotides for its assembly just as does DNA, so it stands to reason it could work for Ebola as well as HIV. In any case, it seems to be working, since the chance of this large a proportion of patients surviving otherwise, without treatment, would be quite unlikely.  
.
Originally posted to wilderness voice on Sat Sep 27, 2014 at 10:59 AM PDT.

Also republished by Good News.

Tags Ebola HIV Lamivudine nucleoside Recommended

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Last Updated on Saturday, 11 October 2014 11:04
 
C.88-Mimétisme moléculaire entre le core du virus de l'hépatite C,le ligand de Fas, la phalloïdine PDF print email
Written by MKG Tran   
Saturday, 27 September 2014 09:48
There are no translations available.

C.88-Mimétisme moléculaire entre le core du virus de l'hépatite C,le ligand de Fas, la phalloïdine et les flavones/flavanols hépato-protecteurs(sibilinine de Sibybum Marianum, vitexine de Desmodium adscendens)
 
C.87- PDF print email
Written by TRAN Guy Mong Ky   
Sunday, 22 December 2013 14:27
There are no translations available.

Hebergeur d'image
Last Updated on Friday, 17 October 2014 18:27
 
C.86-Breast Cancer And Virus: Molecular Homology Between Human Mammary Tumor Virus 3’Orf And Scorpio PDF print email
Written by TRAN Guy Mong Ky   
Monday, 09 December 2013 12:27
There are no translations available.

C.86-Breast Cancer And Virus: Molecular Homology Between Human Mammary Tumor Virus 3’Orf And Scorpion Toxin, A Ligand Of Voltage-Gated Sodium Na+ Channel. Omega 3, A Na+ Channel Modifier, Reduces The Risk Of Metastatic Breast Cancer.

Présentation Poster au 5° congress européen de virology (Lyon Septembre 2013) REF 017 Category: 03.Innate immunity against viruses


Breast cancer has multiple etiologies: Many virus were implicated [Epstein-Barr virus, Human oncogenic Papillomavirus, Adenovirus, Simian Virus 40 (SV40)]. Some discrepancies (Park DJ, 2011) can be relevant to this multiplicity of viruses. Other factors can be unrecognized: Genetics, radio-activity, aluminium, genetically modified organisms.

 

The human homologue of Mouse Mammary Tumor Virus (MMTV) (Bittner JJ, 1936), re-called

Human Mammary Tumor Virus (HMTV), was found in human Breast Cancer (BC), in variable % of cases:  74% in Tunisia, 42% in Australia, 38% in Italy, 36% in United States, 31% in Argentina, 0.8% in Vietnam (Levine PH, 2004). This geographical disparity may depend on various factors, such as the degree of mouse infection by MMTV (Stewart TH, 2000; Szabo S, 2005). The host susceptibility or resistance to MMTV is depending on the species genetic background, particularly the T Cell Receptor (TCR) Vbeta.

The MCF-7 and MDA-MB-231 breast cancer cell lines were demonstrated to be HTMV-positive (Wang Y, 1995); when injected in nude mice, they induce metastatic breast cancer (Shafie SM, 1980; Price JE, 1990). In 123 treated breast cancers, Bougnoux P (1995) found after 48 months 70% metastasis if the breast fat alpha-linolenic acid (omega-3 precursor) level was low (9% if it was high): Thus, omega-3 (18:3n-3) protects against metastasis.

 

 

As omega-3 modifies the voltage-gated Na+ channel (NaCh) (Xiao YF, 2001; Banu I, 2006), we looked for a NaCh ligand (scorpion toxin) in HMTV.

METHODS: Amino Acid (AA) sequence comparison.

RESULTS: we found a molecular homology between HMTV 3’orf and scorpion toxin chimera (Possani LD, 2000)/Euscorpius Flavicaudus (AAT76439) (58-71) implicated in development:

 

 

We demonstrated the HMTV oncogenicity by the discovery of 2 major oncogenes in the 3'ORF:

Mdm2, the p53 ligand (Tran GMK, 2004) and Notch-1 (Tran GMK, 1998). Furthermore,  MMTV is a hormonal virus, because it integrated upstream of and activated Aromatase (Int-5), the estrogen synthetase (Tekmal RR ,1997).

 

 

 

CONCLUSION

HTMV has 2 major oncogenes (mdm2, the p53 ligand, and Notch-1) and is a hormonal virus integrating upstream of and activating aromatase, the estrogen synthetase. HTMV 3’orf contains a scorpion toxin, explaining the metastasis protection conferred by omega-3, a NaCh blocker.The omega-3-rich soya diet in Asia, added to the low HTMV frequency in Asia (Japan, China, Vietnam), may explain the low asian breast cancer prevalence. We suggest to use omega-3 in association with  chemotherapy in metastatic breast cancer; and study other second generation NaCh ligands (Tran GMK, Allostery EMBO Conf 2013; Djamgoz MBA, 2006).

Green tea (Yang CS, 2010) associated with mushrooms were also very interesting alicaments (breast cancer risk reduction of 89%, with an odds ratio = 0,11 (Zhang M, 2009). Corossol (graviola) was re-assessed: It down-regulates EGFR expression (Dai Y, 2011).

BIBLIOGRAPHY

Banu I, Fraser SP, Djamgoz MBA. Docosahexaenoic acid (omega-3) blocks voltage-gated sodium channel activity and migration of MDA-MB-231 human breast cancer cells. Int J Biochem Cell Biol 2006, 38: 2173–82. Bittner JJ. Some possible side effects of nursing on the mammary tumor incidence in mice. Science. 1936, 84: 162. Bougnoux P, Lhuillery C. Acides gras polyinsaturés et cancérogenèse mammaire. In : Nutrition et cancer. CERIN Symposium, Paris, 1995: 119-32. Dai Y, Hogan S, Schmelz EM et al. Selective Growth Inhibition of Human Breast Cancer Cells by Graviola Fruit Extract In Vitro and In Vivo Involving Downregulation of EGFR Expression. Nutrition Cancer 2011, 63:795-801. Djamgoz MBA and Banu I. Dietary Compounds As Anti-cancer Agents: A Preliminary Evaluation of Ion Channels And Membrane Excitability As Possible Target Mechanisms. Turkish J Biochem 2006, 31: 57–68. El Ayeb M, Darbon H, Bahraoui EM et al. Differential effects of defined chemical modifications on antigenic and pharmacological activities of scorpion alpha and beta toxins. Eur J Biochem. 1986, 155: 289-94. Kharrat R, Darbon H, Rochat H et al. Structure/activity relationships of scorpion alpha-toxins. Multiple residues contribute to the interaction with receptors. Eur J Biochem. 1989, 181: 381-90. Levine PH, Pogo BG, Klouj A et al. Increasing evidence for a human breast carcinoma virus with geographic differences. Cancer. 2004, 101: 721-6.  Park DJ, Southey MC, Giles GG, Hopper JL. No evidence of MMTV-like env sequences in specimens from the Australian Breast Cancer Family Study. Breast Cancer Res Treat. 2011, 125: 229-35.  Possani LD, Merino E, Corona M et al. Peptides and genes coding for scorpion toxins that affect ion-channels. Biochimie. 2000, 82: 861-8. Review. Price JE, Polyzos A, Zhang RD et al. Tumorigenicity and Metastasis of Human Breast Carcinoma Cell Lines in Nude Mice. Cancer Res 1990, 50: 717-21. Shafie SM, Liotta LA. Formation of metastasis by human breast carcinoma cells (MCF-7) in nude mice. Cancer Lett. 1980, 11: 81-7. Stewart TH, Sage RD, Stewart AF et al. Breast cancer incidence highest in the range of one species of house mouse, Mus domesticus. Br J Cancer. 2000, 82: 446–51. Szabo S, Haislip AM, Garry RF. Of mice, cats, and men: Is human breast cancer a zoonosis? Microsc Res Tech. 2005, 68: 197-208. Tekmal RR, Keshava N. Role of MMTV integration locus cellular genes in breast cancer. Front Biosci. 1997, 2: d519-26. Tran MKG, Kirkiacharian S, Caprani A, Maurisson G. Molecular mimicry between HIV 1 Nef and human mdm2 ( mouse double minute 2), a ligand of p53, the major suppressor protein in oncology. XV Int AIDS Conf, Bangkok (Thailand), 2004: Abstr. WePeA5599.  Tran MKG, Kirkiacharian S. MMTV (Mouse Mammary Tumor Virus) 3'ORF mimicks the EGF family: EGF, Heregulin (c-Erb2 ligand), proto-oncogene Notch. Eurocancer 1998 (Boiron M, Marty M Ed). Paris, John Libbey Eurotext. p177 (P20). books.google.fr/books?isbn=2742002170. Tran GMK, Caprani A. Voltage-gated sodium Na+ channel allostery as the basis for the scorpion venom model of AIDS: Molecular homology between between spider toxin and HIV-2, and scorpion toxin and HIV-1 envelope gp41 sequence SWSNKS. Allostery EMBO Institut Pasteur Conf 2013, Sept 14-17, Paris. (On the site of : Positifs.org). Wang Y, Holland JF, Bleiweiss IJ et al. Detection of mammary tumor virus env gene-like sequences in human breast cancer. Cancer Res. 1995, 55: 5173-9. Xiao YF, Wright SN, Wang GK et al. Fatty acids suppress voltage-gated Na+ currents in HEK293t cells transfected with the alpha-subunit of the human cardiac Na+ channel. Proc Natl Acad Sci U S A. 1998, 9: 2680-5.  Yang CS & Wang X . Green Tea and Cancer Prevention. Nutrition Cancer 2010, 62: 931-7. Zhang M, Huang J, Xie X, Holman CD. Dietary intakes of mushrooms and green tea combine to reduce the risk of breast cancer in Chinese women. Int J Cancer. 2009, 124: 1404-8. Acknowledgements: Association Positifs.

 

 

 

Last Updated on Saturday, 28 December 2013 14:35
 
C.85-Thai AIDS Vaccine RV 144: Molecular Homology Between HIV-1 Gp 120 Envelope First Conserved Regi PDF print email
Written by TRAN Guy Mong Ky   
Monday, 09 December 2013 12:13
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C.85-Thai AIDS Vaccine RV 144: Molecular Homology Between HIV-1 Gp 120 Envelope First Conserved Region C1, Which Induces IgA Antibodies Increasing AIDS Risk, And The Complement Receptor CR1

Thailand RV 144 vaccine, despite gp120 V1/V2 loops neutralizing IgG, has a low 31% efficacy, mitigated by IgA antibodies against the first conserved region C1 (odds ratio 3.15) (Haynes BF, 2012). We analyse the biological significance of C1 by Basic Local Alignment Search Tool Protein (BLASTP) and visual Amino Acid (AA) sequences comparison: We screened C1 of the vaccine 2 Thailand strains and all HIV-1 strains (HIV Sequence Compendium 2012 Kuiken C, Los Alamos) on Homo Sapiens and found a molecular homology between C1 (AA 112-122) and Complement Receptor type 1 CR1 (CD35) isoform S (AA 2089-2099), in the CCP 32 [NP_000642]; the  corresponding numbering of allotype F is  AA 1639-1649, in the Sushi 25 [P17927]:
C1                                 112-WDQSL KP CVKL-122
C1 (strain CRF 37_cpx) (Powell RL, 2007) 112-WGPKL KP CVKL-122
CR1 isoform S  CCP 32              2089-WGPKL(H,P)CS RV-2099

 

 

 

Domain structure of human complement receptor CR1 and its most common cell expression profile. Human CR1 F allotype contains 30 Short Consensus Repeats (SCRs), each depicted by spheres. Indicated in red are the SCRs mediating binding to the C3b fragment (Hea JQ, 2008).

 

 

 

The tip of the complement receptor CR1 loop (Proline P2095) is read in retro inverso : 2096-(H,P)-2095, instead of 2095-PH-2096.

Such tip inversion exists: Epidermal Growth Factor (EGF) and Transforming Growth Factor-alpha (TGF-a) bind to the same EGF Receptor, despite different tip linear sequence, but in 3D have superimposed loop tip AAs (E and V):
Rat EGF          24 - E S V - 26
TGF-alpha      26 -(E,Q,V)- 24
Anti-C1 IgA harmfulness is explained by Wagner C (2006): Anti-complement receptor CR1 antibodies profoundly inhibit T cell proliferation by inhibiting Interleukin-2 (IL-2)/Interferon-gamma synthesis and IL-2 efficacy, explaining IL-2 clinical trials failure despite T4 cell rise (Pett SL, 2010). CR1 is decreased in lung tuberculosis (Senbagavalli P, 2008). It acts on macrophages and dendritic cells.

Conclusion

An AIDS vaccine must avoid anti-C1 IgA antibodies, because C1 is a molecular mimetic of CR1 and therefore the cross-reactive anti-C1 IgA are anti-CR1 auto-antibodies which profoundly inhibit T cell proliferation. These auto-antibodies could also promote lung tuberculosis. We advocate an AIDS vaccine devoid of this envelope gp120 first constant region C1 deleterious epitope to ameliorate the 31% efficacy observed with the Thai RV 144 vaccine.

An AIDS therapeutic vaccine (as was the case for Pasteur anti-rabies vaccine) would be more rapid to develop, step by step, than a classical prophylactic vaccine: The rapidity of a therapeutic vaccine is calculated in months, whereas for a prophylactic vaccine, each trial would take dozen of years. The same therapeutic vaccine, when finally successful, can be then converted in a prophylactic vaccine (following the anti-rabies vaccine example).

 

BIBLIOGRAPHY

 

Haynes BF, Gilbert PB, McElrath MJ et al. Immune-correlates analysis of an HIV-1 vaccine efficacy trial. N Engl J Med. 2012, 366: 1275-86. Hea JQ, Wiesmannb C, van Lookeren Campagnea M. A role of macrophage complement receptor CRIg in immune clearance and inflammation. Mol Immunol 2008, 45: 4041–47. HIV Sequence Compendium 2012 Kuiken C, Foley B, Leitner T, Apetrei C, Hahn B, Mizrachi I, Mullins J, Rambaut A, Wolinsky S, and Korber B, Eds. Published by Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, NM, LA-UR 12-24653.  Krych-Goldberg M, Moulds JM, Atkinson JP. Human complement receptor type 1 (CR1) binds to a major malarial adhesin. Trends Mol Med. 2002, 8: 531-7. Review. Pett SL, Kelleher AD, Emery S. Role of interleukin-2 in patients with HIV infection. Drugs. 2010 Jun 18;70(9):1115-30. Review. Powell RL, Zhao J, Konings FA et al. Circulating recombinant form (CRF) 37_cpx: an old strain in Cameroon composed of diverse, genetically distant lineages of subtypes A and G. AIDS Res Hum Retroviruses. 2007, 23: 923-33. Senbagavalli P, Geetha ST, Karunakaran K et al. Reduced erythrocyte CR1 levels in patients with pulmonary tuberculosis is an acquired phenomenon. Clin Immunol. 2008, 128: 109-15. Wagner C, Ochmann C, Schoels M et al. The complement receptor 1, CR1 (CD35), mediates inhibitory signals in human T-lymphocytes. Mol Immunol. 2006, 43: 643-51. Acknowledgements: Association Positifs.



 

 

 

 

 

 

 


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